Our products

Chronolife is an healthcare artificial intelligence company that develops remote monitoring and predictive solutions

HOTS – PREDICTIVE ALGORITHM

PREDICTIVE ALGORITHM

What is HOTS?

What is HOTS?

(Hierarchy of Event-Based Time Surfaces)

Event based predictive algorithm capable of analyzing complex data flows on low bandwidth such as smartphones or tablets, for detection of relevant events & prediction.

HOTS can be ported and integrated on third-party medical devices and mobile platforms for local edge computing and alert generation.

Our core innovation is based on patented machine learning algorithm, which uses a biomimetic approach of computing. Known as HOTS, forHierarchy Of event-based Time Surfaces”, the technology has scientifically been validated using computer vision applications. It was recognized to have enormous potential for medical decision support systems because this innovative algorithm can learn to classify complex patterns. HOTS can process any type of incoming signal thanks to its neuromorphic* process. This neuromorphic approach considerably reduces the bandwidth requirement and enables real-time embedded computation leading to a breakthrough of conducting big-data analysis on a regular smartphone.


ADVANTAGES

HOTS benefits and competitive advantages:

 

Perform data fusion for complex, multiple and continuous data streams

 

 

Base its analysis on pattern deviations/global state changes,

 

 

Generate alerts to predict any changes in a person’s health status*

 

 

Can run on low-power processors and use limited bandwidth.

 

 

HOTS can therefore be used for a variety of use cases and applications, on different devices and connected objects (smartphones, tablets, smartwatches and connected devices).


HOW DOES IT WORK

 

 

*The clinical trial to demonstrate the safety and efficacy of HOTS to predict Worsening Heart Failure is ongoing with over 500+ patients in Europe.

NEXKIN – CUSTOM SOLUTION

CUSTOM SOLUTION

What about this product?
Thoracic respiration
Thoracic respiration
Thoracic respiration
Physical activity
Physical activity
Physical activity
.
Abdominal respiration
Abdominal respiration
Abdominal respiration
Temperature
Temperature
Temperature
Electrocardiogram
Electrocardiogram
Electrocardiogram
Pulmonary impedance
Pulmonary impedance
Pulmonary impedance
Pulmonary impedance
Pulmonary impedance
Pulmonary impedance
Electrocardiogram
Electrocardiogram
Electrocardiogram
Temperature
Temperature
Temperature
Electrocardiogram
Electrocardiogram
Electrocardiogram

What about this product?

Allows to develop a customized solution according to specific needs of the user. The solution (CE & FCC) is based on a smart shirt which is  washable & comfortable with companion application to collect and transmit data on six different physiological parameters to certified servers for healthcare. The solution has been designed for prevention programs and for example to support ageing in place and for occupational hazard prevention. It can also accompany rehabilitation programs after an illness/injury and support athletes’ performance analysis.

Thoracic respiration
Thoracic respiration
Physical activity
Physical activity
Abdominal respiration
Abdominal respiration
Temperature
Temperature
Electrocardiogram
Electrocardiogram
Pulmonary impedance
Pulmonary impedance

APPLICATIONS


HOW DOES IT WORK

The solution offers the opportunity to adapt each of the element to meet specific needs.

The data collected is encrypted and transmitted to the user smartphone application via a BTLE (BlueTooth Low Energy) link before being re-encrypted and transmitted to secure servers via Wi-Fi or 3G/4G networks. Collected data is then made available through a web interface for more in-depth analysis.

The solution is provided with a demo application as well as an SDK (Software Development Kit) for customers willing to develop their own application:

Smart shirt
Smart shirt
Connected shirt that continuously collects 6 different physiological parameters
App
App
Software Development Kit provided to adapt app interface & alerts.
Hosting server
Hosting server
Accredited medical data hosting servers.
Web interface
Web interface
Secure access to data.

 

 

KEESENSE – MEDICAL MONITORING SOLUTION

MEDICAL MONITORING SOLUTION

What about this product?
Thoracic respiration
Thoracic respiration
Thoracic respiration
Physical activity
Physical activity
Physical activity
Abdominal respiration
Abdominal respiration
Abdominal respiration
Temperature
Temperature
Temperature
Electrocardiogram
Electrocardiogram
Electrocardiogram
Pulmonary impedance
Pulmonary impedance
Pulmonary impedance
Pulmonary impedance
Pulmonary impedance
Pulmonary impedance
Electrocardiogram
Electrocardiogram
Electrocardiogram
Temperature
Temperature
Temperature
Electrocardiogram
Electrocardiogram
Electrocardiogram

What about this product?

Washable and comfortable medical device (CE Class IIa) in form of a t-shirt with multiple embedded sensors & electrodes designed to capture continuous data on 6 physiological parameters. Data is transmitted to health data hosting servers and made available to Healthcare Professionals for analysis. The multiparametric solution allows care givers and healthcare professionals to accompany their patients all along the continuum of care for RPM (Remote Patient Monitoring) or therapeutic efficiency programs.

Thoracic respiration
Thoracic respiration
Physical activity
Physical activity
Abdominal respiration
Abdominal respiration
Temperature
Temperature
Electrocardiogram
Electrocardiogram
Pulmonary impedance
Pulmonary impedance

ADVANTAGES OF THE SOLUTION

 


How does it work

This medical device consists of 4 components: a smart shirt and its companion smartphone application, a web interface and hosting services.

The shirt connects to the smartphone via a QR Code. Data is transferred to the smartphone by BTLE (BlueTooth Low Energy) and to a secure server through 3G/4G Wi-Fi to be accessed by medical personnel through a web interface, integrated into the healthcare professional’s software platform.

Smart shirt
Smart shirt
Connected shirt that continuously collects 6 different physiological parameters
App
App
A simple and user-friendly interface for fast connection and data collection.
Hosting server
Hosting server
Accredited medical data hosting servers.
Web interface
Web interface
Secure access to data.
PREDICTIVE SOLUTION

PREDICTIVE SOLUTION

What about this product?
Thoracic respiration
Thoracic respiration
Thoracic respiration
Physical activity
Physical activity
Physical activity
Abdominal respiration
Abdominal respiration
Abdominal respiration
Temperature
Temperature
Temperature
Electrocardiogram
Electrocardiogram
Electrocardiogram
Pulmonary impedance
Pulmonary impedance
Pulmonary impedance
Pulmonary impedance
Pulmonary impedance
Pulmonary impedance
Electrocardiogram
Electrocardiogram
Electrocardiogram
Temperature
Temperature
Temperature
Electrocardiogram
Electrocardiogram
Electrocardiogram

What about this product?

Wearable medical device (CE Class IIb*1) designed to remotely monitor and predict Worsening Heart Failure by leveraging Chronolife’s powerful algorithm technology HOTS (Hiearchy Of event-based Time-Surfaces). It does this through the collection of multiple physiological signals using the smart wearable and the analysis of this data through HOTS on the companion smartphone application.

The T-shirt has fully embedded sensors that record 6 physiological parameters that are clinically relevant for the assessment of cardiovascular and respiratory status. The T-shirt is designed to be used as a daily garment and is fully washable. It also includes a non-removable rechargeable battery, a memory card and a Bluetooth interface. All electronic components have been sealed in water-resistant coatings.

Thoracic respiration
Thoracic respiration
Physical activity
Physical activity
Abdominal respiration
Abdominal respiration
Temperature
Temperature
Electrocardiogram
Electrocardiogram
Pulmonary impedance
Pulmonary impedance

Challenges we answer to

Heart failure is a global pandemic affecting at least 26 million people worldwide: Our solution intends to adress the challenges faced by healthcare professionals & patients. The global economic burden of Heart Failure is estimated at $108 billion annually, where Europe accounts for 6.83% and the US for 28.4% of the total*2. With our solution we aim to bring a paradigm shift in healthcare with the goal of improving quality of life, provide better care & reduce costs. Our aim is to accompany doctors & clinicians in a faster & more efficient decision making.

 

Advantages of the solution


How does it work

The T-shirt continuously collects data that is transferred to the smartphone over a simple Bluetooth connection. The multiple physiological data flow collected are directly analyzed by HOTS on the smartphone, without the need for computing on remote servers. HOTS will function to detect and predict an imminent decompensation event*3, alerting the patient and their physician via the smartphone application, with the appropriate recommendations. The data collected by the shirt is also transferred via the smartphone to a secure server where it is saved so patient’s history can be consulted by the healthcare professionals.

 

Smart shirt
Smart shirt
Connected t-shirt that continuously collects 6 different physiological parameters
App
App
Detection & Prediction of Worsening Heart Failure.
Hosting server
Hosting server
Accredited medical data hosting servers.
Web interface
Web interface
Secure access to data.

*1 Ongoing

*2 Lesyuk W, et al. Cost-of-illness studies in heart failure: a systematic review 2004-2016. BMC Cardiovascular Disorders (2018) 18:74.

*3 The clinical trial to demonstrate the safety and efficacy of HOTS to predict Worsening Heart Failure is ongoing with over 500+ patients in Europe.